Figure 8 | Scientific Reports

Figure 8

From: Identification of specialized pro-resolving mediator clusters from healthy adults after intravenous low-dose endotoxin and omega-3 supplementation: a methodological validation

Figure 8

SPM production is increased in human plasma via ω-3 PUFA supplementation and immunologic challenge. (A) Total SPM cluster concentrations in human plasma with ω-3 PUFA supplementation or placebo 1–168 h post intravenous LPS injection; *P < 0.05, **P < 0.01 for ω-3 PUFA supplement group vs. placebo group with one-tailed ratio t-test. (B) Comparison of total SPM cluster concentrations in human plasma at 2 h between separate laboratories. Results are means ± SEM of 3 healthy subjects; *P < 0.05; ns = not statistically different using paired one-tailed ratio t-test.

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