Figure 1

Inactivation of TTI2 and RTEL1 after 3, 6, and 12 wk of silica inhalation. (A–C) TTI2 and (D–F) RTEL1 expression in lung cDNA at 16 hr after a 3, 6, and 12 wk silica inhalation exposure (15 mg/m3, 6 h/d, 5 d/wk). Rats exposed to filtered air served as the controls; n = 8; values are means ± standard error; *significantly different from corresponding air control, p < 0.05.