Figure 6
From: Prickle1 regulates differentiation of frontal bone osteoblasts
Ossification is delayed in the frontal bone primordium. DIG-labeled section in situ hybridization to E12.5 Prickle1+/+ (a–c) and Prickle1Bj/Bj (d–f) littermates. The expression levels of Runx2 (a,d), Alkaline phosphatase (ALP) (b,e) and Osterix (c,f) are decreased in frontal bone primordium of Prickle1Bj/Bj mutants compared with wild-type control embryos. Scale bar in a = 200 μm, and applies to all.
