Table 3 Baseline characteristics of the study subjects according to CRP and body fat percentage stratified by age in women.

From: Gender- and Age-Specific Associations Between Body Fat Composition and C-Reactive Protein with Lung Function: A Cross-Sectional Study

Characteristics

CRP < 75% fat% < 75%

CRP ≥ 75% fat% < 75%

CRP < 75% fat% ≥ 75%

CRP ≥ 75% fat% ≥ 75%

P value (ANOVA)

P value (P trend)

<45 y/o

Number

3034

641

600

570

—

—

Age, years

34.4 (5.3)

34.8 (5.4)

36.4 (5.1)

36.3 (5.2)

<0.001

<0.001

BMI (kg/m2)

20.1 (1.9)

20.8 (1.9)

24.4 (2.1)

25.7 (2.9)

<0.001

<0.001

Waist-to-height ratio

0.44 (0.04)

0.46 (0.04)

0.50 (0.04)

0.53 (0.05)

<0.001

<0.001

Body fat percentage, %

25.9 (4.1)

27.4 (3.6)

34.9 (2.5)

36.6 (3.8)

<0.001

<0.001

Mean arterial pressure (mmHg)

78.9 (9.1)

79.6 (9.2)

81.8 (10.2)

85.0 (12.1)

<0.001

<0.001

Fasting glucose (mmol/L)

4.86 (0.42)

4.91 (0.60)

5.02 (0.46)

5.20 (0.87)

<0.001

<0.001

Total cholesterol (mmol/L)

4.68 (0.79)

4.63 (0.86)

4.82 (0.87)

4.91 (0.88)

<0.001

<0.001

Triglycerides (mmol/L)

0.79 (0.38)

0.94 (0.63)

1.01 (0.62)

1.26 (0.75)

<0.001

<0.001

LDL cholesterol (mmol/L)

2.75 (0.68)

2.78 (0.75)

2.99 (0.74)

3.14 (0.75)

<0.001

<0.001

HDL cholesterol (mmol/L)

1.55 (0.30)

1.45 (0.32)

1.41 (0.28)

1.32 (0.26)

<0.001

<0.001

TG/HDL-C

0.55 (0.36)

0.72 (0.70)

0.78 (0.64)

1.04 (0.81)

<0.001

<0.001

hsCRP (μg/mL)

0.37 (0.23)

3.48 (5.33)

0.51 (0.26)

3.10 (4.17)

<0.001

<0.001

FVC, %predicted

93.1 (12.2)

91.4 (12.5)

95.6 (12.7)

91.8 (12.3)

<0.001

0.836

FEV1, %predicted

95.8 (12.2)

93.1 (12.3)

96.7 (12.7)

93.1 (12.1)

<0.001

0.015

FEV1/FVC

89.2 (6.1)

88.4 (6.4)

87.4 (5.5)

87.7 (5.8)

<0.001

<0.001

Restrictive lung disease, n (%)†

330 (10.9)

84 (13.1)

47 (7.8)

75 (13.2)

0.008

0.664

≥45 y/o

Number

2014

468

465

358

—

—

Age, years

53.5 (6.8)

55.4 (7.0)

55.6 (7.1)

56.6 (7.3)

<0.001

<0.001

BMI (kg/m2)

22.5 (2.2)

23.4 (2.1)

27.4 (2.2)

28.3 (2.7)

<0.001

<0.001

Waist-to-height ratio

0.50 (0.05)

0.52 (0.04)

0.57 (0.04)

0.59 (0.05)

<0.001

<0.001

Body fat percentage, %

29.7 (4.5)

31.2 (3.9)

39.3 (2.9)

40.6 (3.6)

<0.001

<0.001

Mean arterial pressure (mmHg)

86.1 (12.9)

90.4 (12.4)

92.5 (13.0)

94.8 (13.1)

<0.001

<0.001

Fasting glucose (mmol/L)

5.24 (1.03)

5.62 (1.62)

5.49 (1.02)

5.96 (1.93)

<0.001

<0.001

Total cholesterol (mmol/L)

5.34 (0.98)

5.42 (1.11)

5.40 (1.04)

5.55 (0.98)

0.002

0.001

Triglycerides (mmol/L)

1.19 (0.74)

1.67 (2.59)

1.46 (1.19)

1.78 (1.23)

<0.001

<0.001

LDL cholesterol (mmol/L)

3.29 (0.82)

3.39 (0.87)

3.43 (0.86)

3.54 (0.84)

<0.001

<0.001

HDL cholesterol (mmol/L)

1.48 (0.31)

1.34 (0.30)

1.37 (0.27)

1.31 (0.29)

<0.001

<0.001

TG/HDL-C

0.89 (0.74)

1.48 (3.61)

1.17 (1.16)

1.50 (1.30)

<0.001

<0.001

hsCRP (μg/mL)

0.72 (0.48)

5.45 (6.78)

1.01 (0.50)

5.10 (5.21)

<0.001

<0.001

FVC, % predicted

93.9 (14.2)

90.4 (15.0)

91.6 (15.0)

86.5 (15.1)

<0.001

<0.001

FEV1, % predicted

96.0 (14.2)

92.9 (15.0)

94.3 (16.0)

89.5 (15.4)

<0.001

<0.001

FEV1/FVC

86.7 (6.2)

86.8 (6.3)

87.0 (5.6)

86.8 (5.1)

0.888

0.776

Restrictive lung disease, n (%)†

258 (12.8)

89 (19.0)

74 (15.9)

102 (28.5)

<0.001

<0.001

  1. †Chi-squared test or Cochran–Armitage test for trend.
  2. BMI, body mass index; TG, triglycerides; HDL-C, HDL cholesterol; FVC, forced vital capacity; FEV1, forced expiratory volume in 1 s. CRP, C-reactive protein.
  3. Data are presented as mean (SD).
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