Table 1 Immunomodulatory genes selected for further analysis. Genes were filtered based on a fold change ≥ 1.5, p < 0.05, coding transcripts only and the presence of a gene symbol. n.s.: not significant.
Gene | Description | MRx0518LV | MRx0518HK | MRx0518SN | |||
|---|---|---|---|---|---|---|---|
Fold change | p-value | Fold change | p-value | Fold change | p-value | ||
CCL20 | Chemokine (C-C motif) ligand 20 | 20.59 | 1.10e-13 | n.s. | n.s. | 8.22 | 2.06e-11 |
CXCL8 | Chemokine (C-X-C motif) ligand 8 | 4.87 | 5.24e-13 | n.s. | n.s. | 1.56 | 3.03e-05 |
ICAM1 | Intercellular adhesion molecule 1 | 4.03 | 2.03e-09 | n.s. | n.s. | n.s. | n.s. |
NFKBIA | NF-κB inhibitor alpha | 3.99 | 5.51e-08 | n.s. | n.s. | 1.61 | 0.0015 |
TNFAIP3 | TNF alpha-induced protein 3 | 2.95 | 3.58e-10 | n.s. | n.s | n.s | n.s |
CXCL1 | Chemokine (C-X-C motif) ligand 1 | 2.41 | 1.13e-08 | n.s. | n.s | n.s. | n.s |
