Figure 2 | Scientific Reports

Figure 2

From: Interactions of HLA-DR and Topoisomerase I Epitope Modulated Genetic Risk for Systemic Sclerosis

Figure 2

RMSD on time series of HLA-DRs. (A) A variety of HLA-DRs without and (B) with Top1 binding are separately plotted for RMSD of the backbone atoms for HLA-DR/Top1 complex (black), HLA-DR protein (red), binding cleft (blue) and nonameric core sequence of Top1 peptide (green). Distributions of RMSD distance during productive selection of 90–100 ns for HLA free form and complex form are collected as the relative frequency.

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