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Figure 1

From: Application of Autologous Platelet-Rich Plasma on Tooth Extraction Site Prevents Occurence of Medication-Related Osteonecrosis of the Jaws in Rats

Figure 1

Newly formed bone tissue (NFBT) in tooth extraction site and non-vital bone tissue (NVBT) in tissues adjacent to tooth extraction site. (A,B) percentage of NFBT (A) and NVBT (B) in the different experimental groups at 28 postoperative days. (C–J) Photomicrographs showing percentage of NFBT in extraction site previously occupied by mesial root of first molar in groups (C,D,G,H) and NVBT in areas adjacent to extraction site (E,F,I,J) in VEH (C,E), VEH-PRP (D,F), ZOL (G,I) and ZOL-PRP (H,J). Symbols: bt, bone tissue; black arrows, osteocytes; ct, connective tissue; ii, inflammatory infiltrate; nvb, non-vital bone; white arrows, empty lacunae or occupied by necrotic remains of osteocytes; †Statistically significant difference in relation to VEH; ‡Statistically significant difference in relation to VEH-PRP; Statistically significant difference in relation to ZOL. Staining: HE. Original magnification: (C,D,G,H) 100×; (E,F,I,J) 250×. Scale bars: (C,D,G,H) 250 μm; (E,F,I,J) 100 μm.

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