Table 2 Top 20 down-regulated genes in ΔrgsD strain relative to WT strain (>4.0-fold, p < 0.01).

From: RgsD negatively controls development, toxigenesis, stress response, and virulence in Aspergillus fumigatus

Gene Symbol

Gene Name

Protein Name

Log2FC

p-value

Normal

FDR

CADAFUAG00009615

AFUA_7G05050

hypothetical protein

−7.238

0.000

0.004

CADAFUAG00009586

AFUA_7G05490

conserved hypothetical protein

−6.323

0.000

0.004

CADAFUAG00009591

AFUA_7G04850

aldo-keto reductase

−5.825

0.000

0.025

CADAFUAG00002129

AFUA_6G09610

nonribosomal peptide synthase

−5.753

0.000

0.002

CADAFUAG00001516

AFUA_6G00260

phosphatidylserine decarboxylase family protein

−5.45

0.000

0.000

CADAFUAG00009416

AFUA_7G05060

MgtC/SapB family membrane protein

−5.267

0.000

0.005

CADAFUAG00008526

AFUA_4G09930

conserved hypothetical protein

−5.113

0.000

0.018

CADAFUAG00009661

AFUA_7G06270

cyanamide hydratase

−5.011

0.000

0.000

CADAFUAG00009491

AFUA_7G04840

hypothetical protein

−4.951

0.000

0.033

CADAFUAG00000328

AFUA_3G03570

67 kDa myosin-cross-reactive antigen family protein

−4.895

0.000

0.000

CADAFUAG00002126

AFUA_6G09745

conserved hypothetical protein

−4.607

0.000

0.022

CADAFUAG00003719

AFUA_2G06000

NAD + dependent glutamate dehydrogenase

−4.56

0.000

0.017

CADAFUAG00000008

AFUA_3G02060

MFS multidrug transporter

−4.444

0.000

0.000

CADAFUAG00001599

AFUA_6G11980

exo-beta-1,3-glucanase

−4.422

0.002

0.025

CADAFUAG00001455

AFUA_4G03250

hypothetical protein

−4.418

0.000

0.000

CADAFUAG00001244

AFUA_7G00960

extracellular cysteine-rich protein

−4.34

0.000

0.000

CADAFUAG00000998

AFUA_8G02280

C6 transcription factor

−4.284

0.000

0.008

CADAFUAG00007109

AFUA_1G11350

MFS transporter of unkown specificity

−4.275

0.000

0.042

CADAFUAG00002750

AFUA_5G00410

conserved hypothetical protein

−4.227

0.000

0.008

CADAFUAG00009533

AFUA_7G05190

MFS alpha-glucoside transporter

−4.072

0.003

0.000