Table 3 Frequencies of immunoglobulins against HEV and clinical outcomes in the two control groups (healthy controls and HIV-monoinfected patients) and HIV/HCV-coinfected patients.

From: Prevalence of hepatitis E infection in HIV/HCV-coinfected patients in Spain (2012–2014)

 

IgM anti-HEV Ab.

IgG anti-HEV Ab.

Acute hepatitis E

Resolved hepatitis E

Exposure to HEV

Healthy controls

0 (0%)

2 (6.7%)

0/30 (0%)

2/30 (6.7%)

2/30 (6.7%)

HIV-monoinfected patients

3 (8.3%)

4 (11.1%)

3/36 (8.3%)

3/36 (8.3%)

6/36 (16.7%)

HIV/HCV-coinfected patients

10 (5.1%)

38 (19.2%)

10/198 (5.1%)

34/198 (17.2%)

44/198 (22.2%)

p-value (HC vs. HIV)

0.505

0.845

0.514

0.760

0.389

p-value (HC vs. HIV/HCV)

0.710

0.127

0.721

0.230

0.082

p-value (HIV vs. HIV/HCV)

0.692

0.295

0.692

0.277

0.560

  1. Statistics: Values expressed as number of cases (%). P-values were calculated by chi-squared test or Fisher’s exact test as required. Abbreviations: HEV, hepatitis E virus; HC, healthy controls; HCV, hepatitis C virus; HIV-1, human immunodeficiency virus type 1.