Figure 4

Tumor resection partially restores tumor-induced increases in basal body temperature and restores hyperthermic responses after LPS injection. Mean (±SEM) baseline body temperature 24 h before LPS injection (A) and relative body temperature change in response to LPS injection (B). *p ≤ 0.05 tumor bearing relative to surgical control mice injected with LPS; #p ≤ 0.05 tumor-bearing relative to –resected mice injected with LPS; &p ≤ 0.05 tumor-resected relative to surgical control mice injected with LPS by repeated measures ANOVA (n = 7–8 mice/group).