Table 2 The demographic data, characteristics of ICGA and OCTA examinations, and treatment response between the 3 groups of distinct branching vascular network (BVN) morphology.

From: Characterizing Branching Vascular Network Morphology in Polypoidal Choroidal Vasculopathy by Optical Coherence Tomography Angiography

 

Type 1 “Trunk” (n = 21)

Type 2 “Glomeruli” (n = 15)

Type 3 “Stick” (n = 9)

P-Value

Age (y/o)

68.0 ± 7.6

69.7 ± 7.3

65.8 ± 7.3

0.469*

Gender (Female)

52.4% (11)

13.3% (2)

22.2% (2)

0.036

Treatment Naïve

52.4% (11)

60.0% (9)

55.6% (5)

0.902

Presence of Drusens

66.7% (14)

33.3% (5)

22.2% (2)

0.037

Submacular hemorrhage

47.6% (10)

53.3% (8)

55.6% (5)

0.903

ICGA-BVN

95.2% (20)

93.3% (14)

44.4% (4)

0.001

Presence of Feeder Vessel

76.2% (16)

60.0% (9)

22.2% (2)

0.022

OCTA-Polyps (Manual)

90.5% (19)

100.0% (15)

77.8% (7)

0.178

OCTA-SFCT (μm)

195.5 ± 66.6

239.5 ± 89.7

284.3 ± 80.1

0.019*,‡

OCTA-CRT (μm)

270.6 ± 60.5

282.5 ± 78.7

259.1 ± 49.8

0.691*

OCTA-BVN area (mm2)

0.919 ± 0.517

0.667 ± 0.381

0.404 ± 0.211

0.021*

BCVA at diagnosis (LogMAR)

0.910 ± 0.730

0.544 ± 0.357

0.530 ± 0.496

0.117*

BCVA post-PDT 6 m (LogMAR)

0.738 ± 0.656

0.476 ± 0.325

0.503 ± 0.458

0.316*

OCTA-SRF recurrence

28.6% (6)

80.0% (12)

88.9% (8)

0.001

PDT Re-Treatment rate

28.6% (6)

40.0% (6)

55.6% (5)

0.368

  1. *One-way ANOVA, Scheffer test if p < 0.05, Chi-square and Fisher’s exact test. Post Hoc: p = 0.023, between Type 1 and 3. §Post Hoc: p = 0.019, between Type 1 and 3, SFCT: subfoveal choroidal thickness, SRF: subretinal fluid, CRT: central retinal thickness, PDT: photodynamic therapy.