Table 2 The demographic data, characteristics of ICGA and OCTA examinations, and treatment response between the 3 groups of distinct branching vascular network (BVN) morphology.
Type 1 “Trunk” (n = 21) | Type 2 “Glomeruli” (n = 15) | Type 3 “Stick” (n = 9) | P-Value | |
---|---|---|---|---|
Age (y/o) | 68.0 ± 7.6 | 69.7 ± 7.3 | 65.8 ± 7.3 | 0.469* |
Gender (Female) | 52.4% (11) | 13.3% (2) | 22.2% (2) | 0.036† |
Treatment Naïve | 52.4% (11) | 60.0% (9) | 55.6% (5) | 0.902† |
Presence of Drusens | 66.7% (14) | 33.3% (5) | 22.2% (2) | 0.037† |
Submacular hemorrhage | 47.6% (10) | 53.3% (8) | 55.6% (5) | 0.903† |
ICGA-BVN | 95.2% (20) | 93.3% (14) | 44.4% (4) | 0.001† |
Presence of Feeder Vessel | 76.2% (16) | 60.0% (9) | 22.2% (2) | 0.022† |
OCTA-Polyps (Manual) | 90.5% (19) | 100.0% (15) | 77.8% (7) | 0.178† |
OCTA-SFCT (μm) | 195.5 ± 66.6 | 239.5 ± 89.7 | 284.3 ± 80.1 | 0.019*,‡ |
OCTA-CRT (μm) | 270.6 ± 60.5 | 282.5 ± 78.7 | 259.1 ± 49.8 | 0.691* |
OCTA-BVN area (mm2) | 0.919 ± 0.517 | 0.667 ± 0.381 | 0.404 ± 0.211 | 0.021*,§ |
BCVA at diagnosis (LogMAR) | 0.910 ± 0.730 | 0.544 ± 0.357 | 0.530 ± 0.496 | 0.117* |
BCVA post-PDT 6 m (LogMAR) | 0.738 ± 0.656 | 0.476 ± 0.325 | 0.503 ± 0.458 | 0.316* |
OCTA-SRF recurrence | 28.6% (6) | 80.0% (12) | 88.9% (8) | 0.001† |
PDT Re-Treatment rate | 28.6% (6) | 40.0% (6) | 55.6% (5) | 0.368† |