Table 1 Tumor burden calculation performed for different samples using three different methods: (1) from the tumor area segmented manually in 2D images of H&E-stained specimens; (2) from the tumor area segmented using a semi-automated method and micro-CT slices of I2E-stained specimen; and (3) and tumor volume reported as the sum of measurements of all the tumorous areas of all virtual micro-CT slices.
Sample | Tumor burden (%) | ||
---|---|---|---|
H&E histological slice | micro-CT virtual slice | micro-CT volumetric image | |
1a | 6.9 | 7.6 | 16.9 |
2b | 5.9 | — | 20.7 |
3c | 20.5 | 22.8 | 65.8 |
4d | 3.3 | 10.5 | 8.8 |