Table 1 Baseline characteristics of the development cohort and validation cohort.

From: An Equation Based on Fuzzy Mathematics to Assess the Timing of Haemodialysis Initiation

 

Development cohort (n = 1281)

Validation cohort (n = 504)

P

Sex (male, %)

59.9

62.5

0.307

Age (years)

54.0 ± 13.8

53.1 ± 15.1

0.221

Body mass index (kg/m2)

16.7 ± 23.5

16.8 ± 11.2

0.002

Symptoms at the beginning of haemodialysis (yes, %)

  Heart failure

29.1

41.3

<0.001

  Vomiting

26.5

47.2

<0.001

  Oedema (II° and above)

45.0

49.6

0.077

  Uraemic encephalopathy

2.6

4.0

0.119

Diabetes (%)

22.4

29.2

0.003

Laboratory test levels at initiation

  Haemoglobin (g/dL)

8.5 ± 2.1

8.2 ± 2.1

0.033

  Albumin (g/dL)

3.5 ± 0.7

3.5 ± 0.6

0.148

  Blood urea nitrogen (mg/dL)

85.7 ± 5.7

91.5 ± 1.5

0.001

  Serum creatinine (mg/dL)

10.1 ± 4.5

10.0 ± 4.2

0.778

  Uraemia (µmol/L)

467.1 ± 163.1

449.7 ± 157.7

0.143

  Potassium (mmol/L)

4.8 ± 0.9

4.9 ± 0.9

0.012

  Sodium (mmol/L)

138.9 ± 4.3

139.1 ± 4.2

0.063

  Calcium (mmol/L)

2.05 ± 0.32

1.97 ± 0.30

 < 0.001

  Phosphate (mmol/L)

2.0 ± 0.70

2.1 ± 0.70

0.028

eGFR (mL/min/1.73 m2)*

7.8 ± 3.9

7.6 ± 3.5

0.287

  ≤5 (%)

20.1

22.4

 

  5–10 (%)

61.1

60.7

 

  >10 (%)

18.8

16.9

 

Died within 3 years of haemodialysis initiation (%)

12.2

11.3

0.969

  1. Note:The conversion factor for the serum creatinine level in mg/dL to µmol/L is × 88.4; the conversion factor for the blood urea nitrogen level in mg/dL to mmol/L is × 0.357; the conversion factor for the haemoglobin and serum albumin levels in g/dL to g/L is ÷10.
  2. Abbreviation: eGFR, estimated glomerular filtration rate.
  3. *Calculated using the Chinese modified Modification of Diet in Renal Disease equation 7.