Table 1 Splicing events in CD4 T cells: infected vs uninfected (DMSO_I vs DMSO), uninfected treated with ABX464 vs uninfected and untreated (464 vs DMSO) and infected treated with ABX464 vs infected and untreated (464_I vs DMSO_I).

From: Both anti-inflammatory and antiviral properties of novel drug candidate ABX464 are mediated by modulation of RNA splicing

ABX464_NI_VS_DMSO_NI

Gene symbol

Ensembl ID

description

Event type

LINC01119

ENSG00000239332

long intergenic non-protein coding RNA 1119

A3

STMND1

ENSG00000230873

stathmin domain containing 1

Alt exons

ZNF177

ENSG00000188629

zinc finger protein 177

A3

FGF22

ENSG00000070388

fibroblast growth factor 22

A3

AL139035.1

ENSG00000280710

Clone-based

Alt exons

MRPL52

ENSG00000172590

mitochondrial ribosomal protein L52

A5; Alt exons

HCG20

ENSG00000228022

HLA complex group 20 (non-protein coding)

Alt exons

RHBDD2

ENSG00000005486

rhomboid domain containing 2

Alt exons

ABX464_I_VS_DMSO_I

AL157955.2

ENSG00000258826

Clone-based

A3

TMEM147

ENSG00000105677

transmembrane protein 147

RI

COX6C

ENSG00000164919

cytochrome c oxidase subunit 6C

Alt exons

ATIC

ENSG00000138363

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

A5

STMND1

ENSG00000230873

stathmin domain containing 1

Alt exons

GEM

ENSG00000164949

GTP binding protein overexpressed in skeletal muscle

Alt Exons

CDRT15

ENSG00000223510

CMT1A duplicated region transcript 15

A5

WDR72

ENSG00000166415

WD repeat domain 72

A5

SMIM11A

ENSG00000205670

small integral membrane protein 11A

AL

EGLN2

ENSG00000269858

egl-9 family hypoxia inducible factor 2

Alt exons

GNRHR2

ENSG00000211451

gonadotropin releasing hormone receptor 2 (pseudogene)

RI

ZNF584

ENSG00000171574

zinc finger protein 584

A3

LINC01869

ENSG00000180279

long intergenic non-protein coding RNA 1869

A3

DMSO_I_VS_DMSO_NI

CHTF8

ENSG00000168802

chromosome transmission fidelity factor 8

Alt exons

KCTD2

ENSG00000180901

potassium channel tetramerization domain containing 2

A5

ETS1

ENSG00000134954

ETS proto-oncogene 1; transcription factor

A5

RASAL2-AS1

ENSG00000224687

RASAL2 antisense RNA 1

A5

SLC16A9

ENSG00000165449

solute carrier family 16 member 9

Alt exons

RPP40

ENSG00000124787

ribonuclease P/MRP subunit p40

Alt exons