Figure 3 | Scientific Reports

Figure 3

From: A Surface Plasmon Resonance-based assay to measure serum concentrations of therapeutic antibodies and anti-drug antibodies

Figure 3

Effect of IFX on determination of ATI concentration. Aliquots of human serum from healthy volunteers were spiked with commercial ATI, to the final concentrations indicated, and with IFX (CT-P13, final concentration 8 μg/mL) or its vehicle. Serum aliquots were diluted 30-fold, subjected to acidic pretreatment, and injected over immobilised IFX and IgG (the latter for evaluation of non-specific binding). The points indicate the specific SPR signal due to the binding of flowing ATI to immobilised IFX.

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