Figure 3
From: Endocan as a marker of microvascular inflammation in kidney transplant recipients

Immunohistochemistry with endocan antibody. (A) Tissues obtained from patients with clear cell renal cell carcinoma were selected as positive controls and stained with endocan. Diffuse immunoreactivity with endocan was found in vascular structures within tumors. (B,C) No immunoreactivity was observed in renal tissues obtained from patients with normal pathology and T-cell mediated rejection. (D) Positive immunostaining with endocan was observed in proximal tubular cells of tissues obtained from patients with acute antibody-mediated rejection. Other regions, including glomerulus, peritubular capillaries, and interstitium, were negative for endocan staining.