Figure 6

Effect of EWH on hippocampus microglia in Al-treated rats. Activated microglia (arrows) in hippocampus of controls group (A,D), Al at 8.3 mg/kg b.w. (B) and Al at 100 mg/kg b.w. (E), EWH + Al 8.3 (C) and EWH + Al 100 (F) detected with the Iba-1 antibody. Scale bar 50 µm. Average numbers of activate microglia per field (objective X40) of rats treated with AlCl3 at 8.3 (G) or 100 (H), co-treated or not with EWH. Results are expressed as mean ± SD, n = 8, *P < 0.05 compared with their corresponding controls (two-way ANOVA and Bonferroni as post-hoc test).