Figure 7
Alternans module. (a) Tissue averaged fluorescent signal from calcium dye loaded mouse atrium paced at 12.5 Hz, showing distinct alternans behaviour at 0.5–3 s (blue, moderate alternans), and 4–6.5 s (red, large alternans). (b) Representative signals and time averaged alternans maps from tissue during moderate alternans behaviour. Four maps shown correspond to the four measures of alternans available in ElectroMap (see methods and Supplementary Fig. VI). (c) Maps during period of large alternans (4–6.5 s) show increase in alternans amplitude, and clear spatial discordance.
