Figure 3 | Scientific Reports

Figure 3

From: Non-invasive in vivo fluorescence imaging of apoptotic retinal photoreceptors

Figure 3

Live imaging of apoptotic photoreceptors in vivo by retinal imaging. (a) Representative fluorescence images of photoreceptors and fundus images of p25 RCS and WT rats 24 hours after PSVue-550 or HBSS solvent eyedrop application as indicated. (b) Quantification of fluorescence intensity after background subtraction in areas indicated by dashed lines. *P < 0.05 by Student’s t-test. (c) Photoreceptor fluorescence and (d) quantification as in b of fluorescence intensity maxima. *P < 0.05 Student’s t-test. (e) Photoreceptor fluorescence and (f) quantification of areas of fluorescent intensities specific to retinal quadrants. *P < 0.05; two-way ANOVA and Tukey post-hoc test. (b,d,f) All bars show mean ± SEM, n = 3 animals per group.

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