Figure 2
From: Top-down Mass Spectrometry Analysis of Human Serum Autoantibody Antigen-Binding Fragments

The UPLC-TD-HRMS analysis of the reduced 12 intact Fab mixture. (A) The base peak chromatogram (BPC) over the m/z range of 550 to 2,000; (B) selected extracted ion chromatograms (EICs) of light chains (left) and heavy chains (right); (C) MS spectra of representative light chains and 4 heavy chains.