Table 1 Clinical Characteristics.

From: Comparison of Forced and Impulse Oscillometry Measurements: A Clinical Population and Printed Airway Model Study

 

Healthy controls (n = 14)

Asymptomatic smokers (n = 17)

Asthma (n = 73)

p-value

Age (years)

50 (18)

50 (14)

59 (14)

0.018

Sex (% male (n))b

57 (8)

29 (5)

53 (39)

0.276

BMI (kg/m2)

26.2 (4.3)

29.6 (5.9)

30.0 (6.0)

0.089

Smoking pack year history

6 (0)

27.6 (14)

8.5 (8)*

0.0003

GINA treatment step (number per group: 1, 2–4, 5)b

—

—

4, 58, 11

—

ACQ-6

—

—

1.04 (1.05)

—

AQLQ

—

—

5.66 (1.33)

—

FEV1 (L)

3.47 (0.86)

2.95 (0.80)

2.54 (0.85)φ

0.0007

FEV1 GLI score

0.89 (1.21)

−0.02 (0.7)

−0.93 (1.27)φ,*

<0.0001

FVC (L)

4.39 (0.87)

3.65 (1.01)

3.46 (0.87)φ

0.003

FVC GLI score

0.99 (1.40)

−0.09 (0.87)

−0.37 (1.05)¥,φ

0.0002

FEV1/FVC

0.78 (0.05)

0.81 (0.06)

0.71 (0.11)φ,*

0.0003

  1. Definition of abbreviations: BMI: Body Mass Index; GINA: Global Initiative for Asthma; ACQ: Asthma control questionnaire; AQLQ: Asthma quality of life questionnaire; FEV1: Forced Expiratory Volume in the first second; GLI: Global Lung Function Initiative; FVC: Forced Vital Capacity. Data presented as mean (SD), bnumber per group, c: χ2 test p value; One Way ANOVA test followed by Tukey multiple comparison test; ¥p < 0.05 healthy vs. smokers. φp < 0.05 healthy vs. asthma; *p < 0.05 smokers vs. asthma.
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