Table 3 DNA methylation (%) and fetal stage exposure to famine

From: Early-Life Exposure to the Chinese Famine Is Associated with Higher Methylation Level in the INSR Gene in Later Adulthood

Genes locus

Exposed group (n = 75)

Non-exposed group (n = 160)

d a

Effect size

P-valueb

P-valuec

INSR

46.7 ± 7.0

43.4 ± 9.2

3.3

0.20

0.003

0.006

CPT1A

44.1 ± 7.8

45.5 ± 8.8

−1.4

−0.08

0.605

NSd

  1. Abbreviations: INSR, insulin receptor; CPT1A, carnitine palmitoyltransferase 1A.
  2. aAverage absolute difference in DNA methylation between exposed group and non-exposed group.
  3. bLinear regression models were used to compare the difference between exposed group and non-exposed group.
  4. cBonferroni-corrected P-value.
  5. dNo significance.
Back to article page