Figure 5
From: Assessing the effects of Ang-(1-7) therapy following transient middle cerebral artery occlusion
Ang-(1-7) therapy has no effect on microglia number or phenotype at 24 hr following MCAO. (a,b) Ang-(1-7) ICV therapy (1.1 nmol/hr; n = 5) did not change IBA1+ microglia total number or % activated cells within peri-infarct or homotopic contralateral regions 24 hr post MCAO compared to Vehicle (aCSF; n = 6) rats. (c,d) Representative images of IBA1+ microglia staining for vehicle and Ang-(1-7) treated median animals within the peri-infarct, homotopic contralateral and infarct regions. Line diagrams adapted from The Rat Brain in Stereotaxic Coordinates by G. Paxinos and C. Watson, 1998.
