Figure 6
From: Assessing the effects of Ang-(1-7) therapy following transient middle cerebral artery occlusion
Ang-(1-7) IV therapy significantly attenuates cerebral perfusion increase in the contralateral hemisphere over time. (a,b) Ang-(1-7) IV infusion therapy (5 nmol/hr; n = 6) significantly attenuated cerebral perfusion increase observed in the contralateral hemisphere in control treated animals (dH2O; n = 5) (P < 0.05). (c,d) Ang-(1-7) therapy did not change perfusion within the ischaemic core and ischaemic penumbra regions during reperfusion. Data were analysed with mean AUC comparisons followed by unpaired Student’s t test; *P < 0.05 was deemed as significant. Data are expressed as mean ± S.D. % change from baseline.
