Figure 2

Trend of the influence (r2) of BMI (panel a) and parental history of T2D of both parents together (panel b) and of the mother and the father separately (panel c) in type 2 diabetes, according to age at T2D diagnosis, grouped by quartiles. The closed circles and triangles show the information of the main case-control study, and the open circles and triangles show the information of the clinical replica study. The dashed lines in red represent the regression lines of the main case-control study and those in black, the regression lines of the clinical replica study. In panel a, the large circles represent the adjusted BMI, and the small circles represent the raw BMI. In panel c, the circles represent the influence of the mother, and the triangles represent the influence of the father. All regressions were carried out with the Pearson’s correlation test and p-values < 0.01.