Figure 7

Adnectin C and Adnectin C-PAS#1(200) inhibited VEGF-induced migration of HUVECs: (a) inhibition by recombinant proteins on VEGF-induced migration of HUVECs through Transwell membranes. The data is represented as mean ± SD (three replicates); #denotes a significant difference from VEGF group (positive control) (p < 0.0001). Asterisks denote significant differences from the untreated (negative) control (**p < 0.01, ***p < 0.001, ****p < 0.0001); (b) representative photographs of stained membranes indicating both proteins considerably inhibited migration of HUVECs compared to the control (see original photographs in Supplementary Fig. S6).