Figure 3 | Scientific Reports

Figure 3

From: Cross-disease analysis of Alzheimer’s disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases

Figure 3

Integration of AD/T2DM overlapping network with human autophagy network (modified from Behrends, C., Sowa, M. E., Gygi, S. P. & Harper, J. W. Network organization of the human autophagy system. Nature 466, 68–76 (2010)). AD, T2DM and AD/T2DM genes are charted in the functional integration of the autophagy interaction network. In blue are shown the genes validated in the two animal models of AD, in red the genes found in the AD network, in green the genes located in the T2Dm network and in pink the AD/T2DM genes.

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