Figure 5 | Scientific Reports

Figure 5

From: Cross-disease analysis of Alzheimer’s disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases

Figure 5

Altered mRNA expression levels autophagy-related genes in the pre-frontal cortex of hApoE TR mice expressing human ApoE3 or ApoE4 fed with either normal diet (ND) or high carbohydrate diet (HC). (A) Atg3; (B) Gabarapl2; (C) Map1lc3b (D) Ifng; (E) Tnf; (F) Ins2; (G) Gaa; (H) Ctss; (I) Dram1; (J) Atg7; (K) B2m; (L) Rps6kb1; (M) Ctsb; (N) Ctsd. ***p < 0.001;**p < 0.05; *p < 0.05.

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