Table 1 Results of the pathway analysis of the AD network. In bold the pathways in common between the AD and T2DM networks.
p value | q value | Pathway | Source |
|---|---|---|---|
6.75E-13 | 1.40E-11 | Ubiquitin mediated proteolysis - Homo sapiens (human) | KEGG |
5.04E-10 | 8.57E-09 | NOTCH1 Intracellular Domain Regulates Transcription | Reactome |
2.06E-09 | 3.24E-08 | Adaptive Immune System | Reactome |
7.35E-08 | 7.91E-07 | Signaling by NOTCH | Reactome |
2.91E-07 | 2.95E-06 | HDACs deacetylate histones | Reactome |
3.16E-06 | 2.58E-05 | FoxO signaling pathway - Homo sapiens (human) | KEGG |
3.20E-05 | 0.00022031 | Macroautophagy | Reactome |
4.16E-05 | 0.00027593 | Regulation of autophagy - Homo sapiens (human) | KEGG |
4.57E-05 | 0.00028679 | Oxidative Stress Induced Senescence | Reactome |
0.0005419 | 0.00254964 | Activation of NF-kappaB in B cells | Reactome |
0.0006026 | 0.0027859 | Wnt signaling pathway - Homo sapiens (human) | KEGG |
0.0007463 | 0.00336957 | Notch signaling pathway - Homo sapiens (human) | KEGG |
0.0009247 | 0.004095 | Neurotrophin signaling pathway - Homo sapiens (human) | KEGG |
0.0018044 | 0.00728684 | Amyloids | Reactome |
0.0018537 | 0.00745715 | Cytokine Signaling in Immune system | Reactome |
0.0022241 | 0.00861836 | Rap1 signalling | Reactome |
0.002268 | 0.00872443 | Estrogen signaling pathway - Homo sapiens (human) | KEGG |
0.0029791 | 0.01113449 | Chemokine signaling pathway - Homo sapiens (human) | KEGG |
0.0032317 | 0.01194569 | Prolactin signaling pathway - Homo sapiens (human) | KEGG |
0.0050714 | 0.01686197 | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | Reactome |
0.0055406 | 0.01830646 | Signaling by Interleukins | Reactome |
0.0079904 | 0.02504608 | Intrinsic Pathway for Apoptosis | Reactome |
0.0088872 | 0.02728608 | Interferon Signaling | Reactome |
