Table 4 Hazard ratios (with 95% CIs) for variables evaluated as potential predictors of all-cause mortality in the GA cohort.
Variables | n (%) | HR | 95% CI | P value |
|---|---|---|---|---|
Male | 514 (70.9) | 1.00 | Reference | Reference |
Female | 211 (29.1) | 1.13 | 0.71–1.78 | 0.608 |
Age | ||||
1 year increase | 725 (100) | 1.05 | 1.02–1.07 | <0.0001 |
Duration of PD (year) | ||||
<2 | 310 (42.8) | 1.00 | Reference | Reference |
2 ≤ < 4 | 204 (28.1) | 1.80 | 1.06–3.06 | 0.029 |
4 ≤ < 6 | 116 (16.0) | 2.03 | 1.02–4.03 | 0.043 |
6 ≤ < 8 | 57 (7.9) | 3.17 | 1.36–7.37 | 0.007 |
8≤ | 38 (5.2) | 2.27 | 0.88–5.85 | 0.087 |
Type of diabetes | ||||
Type 2 | 637 (87.9) | 1.00 | Reference | Reference |
Type 1 | 88 (12.1) | 1.09 | 0.57–2.11 | 0.782 |
CVD comorbidity | ||||
No | 535 (73.8) | 1.00 | Reference | Reference |
Yes | 190 (26.2) | 2.69 | 1.71–4.24 | <0.0001 |
Smoking | ||||
No | 566 (89.0) | 1.00 | Reference | Reference |
Yes | 70 (11.0) | 1.22 | 0.58–2.59 | 0.592 |
Antihypertensive agent | ||||
User | 551 (83.6) | 1.00 | Reference | Reference |
Non-user | 108 (16.4) | 1.93 | 1.12–3.33 | 0.017 |
HD combination | ||||
No | 553 (76.3) | 1.00 | Reference | Reference |
Yes | 172 (23.7) | 1.01 | 0.58–1.76 | 0.971 |
Residual renal function | ||||
Non-anuric | 429 (79.2) | 1.00 | Reference | Reference |
Anuric | 113 (20.8) | 1.78 | 1.01–3.22 | 0.041 |
Type of dialysate | ||||
2.5% non-user | 367 (56.4) | 1.00 | Reference | Reference |
2.5% user | 284 (43.6) | 2.19 | 1.34–3.59 | 0.002 |
Type of dialysate | ||||
Icodextrin non-user | 302 (46.4) | 1.00 | Reference | Reference |
Icodextrin user | 349 (53.6) | 1.15 | 0.73–1.83 | 0.528 |
Type of treatment | ||||
APD non-user | 346 (53.7) | 1.00 | Reference | Reference |
APD user | 298 (46.3) | 0.74 | 0.48–1.19 | 0.236 |
Total Kt/V | ||||
<1.1 | 55 (11.9) | 3.43 | 1.33–8.83 | 0.011 |
1.1 ≤ < 1.4 | 64 (13.8) | 2.53 | 0.93–6.93 | 0.068 |
1.4 ≤ < 1.7 | 102 (22.0) | 1.00 | Reference | Reference |
1.7 ≤ < 2.0 | 107 (23.1) | 0.74 | 0.27–2.05 | 0.573 |
2.0≤ | 135 (29.2) | 1.02 | 0.41–2.51 | 0.972 |
Body mass index (kg/m2) | ||||
<20.0 | 62 (9.9) | 2.68 | 1.25–5.77 | 0.011 |
20 ≤ < 22 | 102 (16.4) | 1.15 | 0.53–2.94 | 0.708 |
22 ≤ < 24 | 153 (24.5) | 1.00 | Reference | Reference |
24 ≤ < 26 | 123 (19.7) | 0.76 | 0.35–1.64 | 0.488 |
26 ≤ < 28 | 84 (13.5) | 0.94 | 0.41–2.19 | 0.895 |
28≤ | 100 (16.0) | 0.67 | 0.28–1.58 | 0.364 |
Serum albumin (g/dL) | ||||
<2.5 | 47 (6.6) | 12.0 | 5.17–27.9 | <0.0001 |
2.5 ≤ < 3.0 | 141 (19.9) | 1.35 | 0.70–2.57 | 0.365 |
3.0 ≤ < 3.5 | 283 (40.0) | 1.00 | Reference | Reference |
3.5 ≤ < 4.0 | 193 (27.3) | 0.59 | 0.30–1.16 | 0.129 |
4.0≤ | 44 (6.2) | 0.17 | 0.02–1.25 | 0.082 |
Hemoglobin | ||||
1 g/dL increase | 711 (98.1) | 0.71 | 0.59–0.84 | <0.0001 |
C-reactive protein | ||||
1 mg/dL increase | 646 (89.1) | 1.39 | 1.18–1.64 | <0.0001 |
Total cholesterol (mg/dL) | ||||
<130 | 83 (13.5) | 1.26 | 0.58–2.74 | 0.552 |
130 ≤ < 150 | 105 (17.2) | 0.78 | 0.37–1.64 | 0.524 |
150 ≤ < 170 | 124 (20.3) | 1.00 | Reference | Reference |
170 ≤ < 190 | 108 (17.7) | 0.75 | 0.36–1.53 | 0.432 |
190 ≤ < 210 | 89 (14.5) | 0.76 | 0.36–1.63 | 0.492 |
210≤ | 103 (16.8) | 0.23 | 0.08–0.60 | 0.003 |
HDL-cholesterol (mg/dL) | ||||
<30 | 70 (11.8) | 3.18 | 1.49–6.79 | 0.003 |
30 ≤ < 40 | 176 (29.7) | 0.84 | 0.41–1.69 | 0.633 |
40 ≤ < 50 | 148 (25.0) | 1.00 | Reference | Reference |
50 ≤ < 60 | 89 (15.0) | 1.12 | 0.49–2.51 | 0.791 |
60 ≤ < 70 | 59 (10.0) | 0.44 | 0.14–1.39 | 0.165 |
70≤ | 50 (8.5) | 0.41 | 0.11–1.50 | 0.179 |
Calcium (mg/dL) | ||||
<8.0 | 154 (21.7) | 0.72 | 0.29–1.75 | 0.473 |
8.0 ≤ < 8.5 | 159 (22.4) | 0.96 | 0.45–2.03 | 0.918 |
8.5 ≤ < 9.0 | 185 (26.1) | 1.00 | Reference | Reference |
9.0 ≤ < 9.5 | 116 (16.4) | 0.76 | 0.34–1.68 | 0.508 |
9.5 ≤ < 10.0 | 66 (9.3) | 0.78 | 0.29–2.09 | 0.629 |
10≤ | 29 (4.1) | 1.83 | 0.64–5.18 | 0.253 |
Phosphate (mg/dL) | ||||
<4.0 | 107 (14.8) | 1.47 | 0.75–2.88 | 0.258 |
4.0 ≤ < 5.0 | 210 (27.8) | 1.47 | 0.83–2.60 | 0.179 |
5.0 ≤ < 6.0 | 221 (30.5) | 1.00 | Reference | Reference |
6.0 ≤ < 7.0 | 115 (15.9) | 1.04 | 0.51–2.13 | 0.903 |
7.0 ≤ < 8.0 | 58 (8.0) | 1.52 | 0.64–3.58 | 0.335 |
8.0≤ | 22 (3.0) | 0.42 | 0.05–3.39 | 0.418 |
Intact-PTH (pg/mL) | ||||
<60 | 119 (18.3) | 1.42 | 0.61–3.34 | 0.412 |
60 ≤ < 140 | 181 (27.9) | 1.23 | 0.53–2.84 | 0.617 |
140 ≤ < 220 | 151 (23.2) | 1.00 | Reference | Reference |
220 ≤ < 300 | 88 (13.5) | 1.17 | 0.48–2.85 | 0.718 |
300 ≤ < 380 | 44 (6.8) | 0.63 | 0.18–2.12 | 0.461 |
380≤ | 67 (10.3) | 1.71 | 0.52–5.57 | 0.368 |
