Figure 4
From: Identification of a novel scaffold for a small molecule GPR139 receptor agonist
Ca2+ mobilization concentration-response curves of AC4 on GPR139 wild-type (WT) and mutants. Data is shown from a representative experiment (mean ± S.D.) out of three independent experiments performed in duplicate. Data is normalized to the Ca2+ response of buffer (0%) and 100 μM AC4 (100%) on myc-GPR139(WT). Residue numbering in superscript is according to GPCRdb numbering system.
