Figure 5
From: Identification of a novel scaffold for a small molecule GPR139 receptor agonist

Ca2+ mobilization concentration response curves of the most potent AC4 analogs and the inactive analog AC170 in CHO-GPR139 cells. The graphs are mean ± S.D. of representative concentration-response curves out of at least three independent experiments performed in duplicate. Data are normalized to the Ca2+ response of buffer (0%) and 8 μM 1a (100%).