Table 2 Treatments effects in mBACtgDyrk1a cortex.

From: Prenatal treatment with EGCG enriched green tea extract rescues GAD67 related developmental and cognitive defects in Down syndrome mouse models

Protein levels

 

T1

T2

T3

F

P value

F

P value

F

P value

GAD67

Interaction

F (1, 37) = 3,069

P = 0,0881

F (1, 35) = 1,973

P = 0,1689

F (1, 36) = 0,1422

P = 0,7083

Genotype

F (1, 37) = 46,31

P < 0,0001

F (1, 35) = 43,48

P < 0,0001

F (1, 36) = 57,50

P < 0,0001

Treatment

F (1, 37) = 9,028

P = 0,0048

F (1, 35) = 0,4603

P = 0,5020

F (1, 36) = 0,2822

P = 0,5985

GAD65

 

F (1, 40) = 3,202

P = 0,0811

F (1, 41) = 1,956

P = 0,1694

F (1, 37) = 4,310

P = 0,0449

 

F (1, 40) = 35,79

P < 0,0001

F (1, 41) = 32,78

P < 0,0001

F (1, 37) = 30,60

P < 0,0001

 

F (1, 40) = 6,152

P = 0,0174

F (1, 41) = 0,3709

P = 0,5459

F (1, 37) = 5,555

P = 0,0238

VGAT1

 

F (1, 41) = 1,371

P = 0,2489

F (1, 42) = 3,772

P = 0,0594

F (1, 38) = 19,26

P < 0,0001

 

F (1, 41) = 46,83

P < 0,0001

F (1, 42) = 25,28

P < 0,0001

F (1, 38) = 14,04

P = 0,0006

 

F (1, 41) = 23,41

P < 0,0001

F (1, 42) = 2,822

P = 0,1010

F (1, 38) = 22,89

P < 0,0001

GLUR2

 

F (1, 40) = 0,8901

P = 0,3511

F (1, 41) = 0,1540

P = 0,6967

F (1, 37) = 0,4270

P =  = 0,5175

 

F (1, 40) = 0,1568

P = 0,6942

F (1, 41) = 1,520

P = 0,2247

F (1, 37) = 1,577

P = 0,2170

 

F (1, 40) = 1,852

P = 0,1812

F (1, 41) = 2,040

P = 0,1608

F (1, 37) = 0,5287

P = 0,4717

NR1

 

F (1, 39) = 5,218e-006

P = 0,9982

F (1, 41) = 0,6596

P = 0,4214

F (1, 37) = 0,07995

P = 0,7789

 

F (1, 39) = 0,9666

P = 0,3316

F (1, 41) = 6,369

P = 0,0156

F (1, 37) = 1,748

P = 0,1942

 

F (1, 39) = 6,660

P = 0,0137

F (1, 41) = 10,32

P = 0,0026

F (1, 37) = 0,1150

P = 0,7365

NR2A

 

F (1, 41) = 3,851

P = 0,0565

F (1, 42) = 7,293

P = 0,0099

F (1, 37) = 2,626

P = 0,1136

 

F (1, 41) = 0,1100

P = 0,7418

F (1, 42) = 0,2296

P = 0,6343

F (1, 37) = 2,558

P = 0,1183

 

F (1, 41) = 6,238

P = 0,0166

F (1, 42) = 2,058

P = 0,1588

F (1, 37) = 0,7885

P = 0,3803

VGLUT1

 

F (1, 41) = 3,851

P = 0,0565

F (1, 42) = 8,4074

P = 0,0059

F (1, 38) = 2,099

P = 0,1556

 

F (1, 41) = 0,1100

P = 0,7418

F (1, 42) = 0,6196

P = 0,9803

F (1, 38) = 3,150

P = 0,0839

 

F (1, 41) = 6,238

P = 0,0166

F (1, 42) = 3,0801

P = 0,0866

F (1, 38) = 1,129

P = 0,2946

VGAT1/VGLUT1

 

F (1, 41) = 34,80

P < 0,0001

F (1, 42) = 23,99

P < 0,0001

F (1, 38) = 8,279

P = 0,0065

 

F (1, 41) = 8,857

P = 0,0048

F (1, 42) = 19,05

P < 0,0001

F (1, 38) = 21,85

P < 0,0001

 

F (1, 41) = 30,99

P < 0,0001

F (1, 42) = 26,03

P < 0,0001

F (1, 38) = 9,994

P = 0,0030