Table 4 Treatments effects in Dp(16)1Yey cortex.

From: Prenatal treatment with EGCG enriched green tea extract rescues GAD67 related developmental and cognitive defects in Down syndrome mouse models

 

T1

T2

Protein levels

GAD67

Interaction

F (1, 39) = 3,664

P = 0,0629

F (1, 39) = 1,639

P = 0,2080

genotype

F (1, 39) = 1,215

P = 0,2770

F (1, 39) = 4,317

P = 0,0444

Treatment

F (1, 39) = 2,334

P = 0,1346

F (1, 39) = 12,70

P = 0,0010

GAD65

Interaction

F (1, 36) = 7,208

P = 0,0109

F (1, 39) = 2,314

P = 0,1363

genotype

F (1, 36) = 1,156

P = 0,2894

F (1, 39) = 7,347

P = 0,0099

Treatment

F (1, 36) = 0,1360

P = 0,7145

F (1, 39) = 5,090

P = 0,0297

VGAT1

Interaction

F (1, 39) = 0,6701

P = 0,4180

F (1, 42) = 1,942

P = 0,1708

genotype

F (1, 39) = 14,73

P = 0,0004

F (1, 42) = 30,24

P < 0,0001

Treatment

F (1, 39) = 0,9720

P = 0,3302

F (1, 42) = 3,062

P = 0,0874

GLUR2

Interaction

F (1, 38) = 2,145

P = 0,1512

F (1, 39) = 1,447

P = 0,2362

genotype

F (1, 38) = 1,179

P = 0,2845

F (1, 39) = 3,995

P = 0,0526

Treatment

F (1, 38) = 7,807

P = 0,0081

F (1, 39) = 49,44

P < 0,0001

VGLUT1

Interaction

F (1, 34) = 0,2892

P = 0,5942

F (1, 36) = 1,109

P = 0,2993

genotype

F (1, 34) = 2,742

P = 0,1070

F (1, 36) = 6,225

P = 0,0173

Treatment

F (1, 34) = 1,710

P = 0,1998

F (1, 36) = 19,12

P = 0,0001

VGAT1/VGLUT

Interaction

F (1, 32) = 0,8482

P = 0,3639

F (1, 36) = 14,69

P = 0,0005

genotype

F (1, 32) = 19,02

P = 0,0001

F (1, 36) = 60,98

P < 0,0001

Treatment

F (1, 32) = 1,683

P = 0,2038

F (1, 36) = 38,93

P < 0,0001