Figure 6
From: ApoE-fragment/Aβ heteromers in the brain of patients with Alzheimer’s disease
Effect of APOE genotype on the quantity of Aβ forms in the cortex of AD patients. Aβ 18 and 16 kDa measured with PA3 antibody (A) or with 6E10 antibody (B) in the cortex of patients carrying APOE2/3 or APOE4. The number of samples analyzed is indicated in parentheses. Two way ANOVA and Bonferroni post-hoc analyses reveal a significant effect of APOE4-carriers on the production of the 18 kDa form of Aβ/ApoE heteromer with both Aβ antibodies (***p < 0.001).
