Figure 8

Endothelial activation and changes to the refractive index (RI) values of individual cells captured on the LoaD platform. The refractive index (RI) values for (a,b) cell membrane and (c, d) nucleus of (a,c) HUVECs and (b,d) EA.hy296 cells before and after TNF-α (20 ng/ml for 24 h) treatment in the absence or presence of IκBα for 24 h under similar index matching conditions (N = 3, p < 0.05, n = 210 cells).