Figure 5
From: Combined Tissue-Fluid Proteomics to Unravel Phenotypic Variability in Amyotrophic Lateral Sclerosis

Significantly regulated pathways comparing B-ALS versus L-ALS at peptide level in plasma/brain. Volcano plot showing medianFC against significance of enrichment (-log10 adj p-value), highlighting the pathways found to be significantly over- (right side of zero) or under- (left side of zero) represented by the differentially-expressed peptides and proteins in the data set. Filled red circles highlight significant pathway hits (adj p-values = p-values and <0.05).