Figure 3

Stochastic simulation snapshots from the stochastic particle simulation of Model 1 using the efficient ReaDDy simulator26. Simulation time: 3 CPU days. Specification files can be found in the Methods Methods Section supp:readdy. (A) Initial state. All 92 kinetochores are unattached (small blue balls). (B) State after checkpoint deactivation. All kinetochores are attached (small red balls). Activated APC/C molecules are shown in pink.