Figure 6

Left: Reaction network of the reduced SAC Model (Model 2). The meaning of symbols and colors is explained in the legend in the bottom left corner. Right: Concentration over time plot from the stochastic particle simulation of Model 2. During metaphase the level of “Activated Promotor” is low and “Inactivated Promotor concentration is high. They switch fast after the last kinetochore is properly attached (time between dashed lines).