Table 2 Top 10 canonical Ingenuity pathways for the differentially expressed proteins at BCP-ALL relapse.

From: Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures

Gene

P-value

Molecules (Proteins)

Glycolysis I

0.000227

ALDOA, ALDOC, GPI, PGAM1, PGK1, PKM

Gluconeogenesis I

0.000227

ALDOA, ALDOC, GPI, MDH1, PGAM1, PGK1

Pentose Phosphate Pathway

0.001333

G6PD, PGD, TALDO1, TKT

CDP-diacylglycerol Biosynthesis I

0.005917

AGPAT5, CDS2, LPCAT3, MBOAT7

Phosphatidylglycerol Biosynthesis II (Non-plastidic)

0.006806

AGPAT5, CDS2, LPCAT3, MBOAT7

EIF2 Signaling

0.009853

RPL14, RPL17, RPL23A, RPL3, RPL36, RPL7, RPL8, RPS17

Sirtuin Signaling Pathway

0.010153

ACLY, G6PD, H1FX, LDHB, NAMPT, PCK2, PGAM1, PGK1, TIMM9

Adenine and Adenosine Salvage I

0.010567

APRT, PNP

Antigen Presentation Pathway

0.013300

HLA-DRA, HLA-DRB1, TAP2, TAPBP

Pentose Phosphate Pathway (Oxidative Branch)

0.039164

G6PD, PGD

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