Figure 5
From: Complement component 1q subcomponent binding protein in the brain of the rat
Co-localization of C1qbp with oxytocin and glial markers. Double labelling of C1qbp (green) and oxytocin (red) (a1) in the PVN. High magnification demonstrates the co-localization between the markers (a2). Double labelling of C1qbp (green) and astrocyte marker S100 (red) (b1), and C1qbp (green) and microglia marker Iba3 (red) (c1). The high magnification confocal images show the lack of co-localisation between C1qbp and glial cell markers (S100 in b2, Iba3 in c2). C1qbp-ir cells within the lesioned area in the cortex at 72 h following a focal ischemic attack (d). Low magnification panel of the lesioned brain double labelled with C1qbp (green) and Iba1 (red) (d1). The border of the lesion is indicated by white dots. Higher magnification image of a double labelled section indicated that C1qbp (green) co-localizes with Iba1 (red) in the infarct area (d2). The inserted panel of high magnification confocal image demonstrates C1qbp in dot-like structures within an Iba1-positive cell. Scale bars = 500 μm for a1 and d1; 300 μm for (b1 and c1) 100 μm for a2,b2,c2 and d2; 10 μm for inserted panel of d2.
