Table 1 Anthropometric characteristics and treatment details of the participants.

From: Altered proteome of high-density lipoproteins from paediatric acute lymphoblastic leukemia survivors

 

Controls

ALL Survivors

All

Healthy

Unhealthy

N (male)

8 (4)

16 (8)

8 (4)

8 (4)

Age (years)

24.2 ± 2.0

24.3 ± 1.1

23.3 ± 1.6

25.4 ± 1.6

BMI (kg/m2)

23.5 ± 0.8

25.3 ± 1.6

22.3 ± 1.0

28.2 ± 2.7

Waist circumference (cm)

Men

87.0 ± 2.8

86.4 ± 4.9

79.1 ± 7.4

93.8 ± 4.6

Women

80.6 ± 2.7

88.1 ± 7.7

78.6 ± 2.9

97.5 ± 14.5

All

83.8 ± 2.2

87.2 ± 4.4

78.8 ± 3.7

95.6 ± 7.1#

Age at diagnosis (years)

NA

8.5 ± 1.3

10.9 ± 1.8

6.2 ± 1.7#

Event-free remission (years)

NA

13.6 ± 1.6

10.2 ± 1.1

17.1 ± 2.6

Treatments

Chemotherapy only

NA

2

2

0

Without cardioprotection

NA

1

1

0

With cardioprotection

NA

1

1

0

Radiotherapy only

NA

0

0

0

Chemotherapy + radiotherapy

 

12

6

6

Without cardioprotection

 

5

1

4

With cardioprotection

 

7

5

2

Cranial radiotherapy dose (Gy)

0

NA

2

2

0

12

NA

6

4

2

18

 

6

2

4

Protocol administered

DFCI 1987-01

NA

1

0

1

DFCI 1991-01

NA

2

0

2

DFCI 1995-01

NA

3

2

1

DFCI 2000-01

NA

5

4

1

DFCI 2005-01

NA

3

2

1

Risk group

Standard risk

NA

12

7

5

High risk

NA

4

1

3

Corcorticosteroids (mg/m2)

NA

11921

13573

10269

Active smoking

0

3

1

2

  1. Data on anthropometrics were collected on ALL survivors (n = 16) and age- and gender-matched controls (n = 8). All survivors were stratified in 2 groups according to their metabolic status as described in Methods (n = 8/group).
  2. NA, non-applicable.
  3. Results are presented as Mean ± SEM. BMI: body mass index, DFCII: Dana-Farber Cancer Institute, Gy: Gray; #p < 0.05 vs Healthy.