Table 2 Metabolic characterization of the study participants.

From: Altered proteome of high-density lipoproteins from paediatric acute lymphoblastic leukemia survivors

 

Controls

ALL Survivors

All

Healthy

Unhealthy

BP (mmHg)

Systolic

—

124 ± 4

117 ± 4

130 ± 7

Diastolic

—

72 ± 3

66 ± 3

77 ± 5

FBG (mmol/L)

5.1 ± 0.1

4.9 ± 0.1

4.8 ± 0.1

4.9 ± 0.2

OGTT (mmol/L)

30 min

—

8.5 ± 0.4

8.1 ± 0.5

8.9 ± 0.6

60 min

—

7.8 ± 0.6

6.5 ± 0.5

9.2 ± 0.9#

120 min

—

5.9 ± 0.4

5.4 ± 0.3

6.4 ± 0.8

MDA (pmol/ml)

298 ± 49

685 ± 95*

692 ± 172

678 ± 96

CRP (mg/L)

—

1.8 ± 0.5

1.1 ± 0.5

2.5 ± 0.7#

Number of MetS criteria

0

8

8

8

0

1

0

1

0

1

2

0

6

0

6

3

0

0

0

0

4

0

1

0

1

  1. Data on metabolic status were collected on ALL survivors (n = 16) and age- and gender-matched controls (n = 8). ALL survivors were stratified in 2 groups according to their metabolic status as described in Methods (n = 8/group). Mets was defined per the NCEP ATP III (SOURCE), with the following cut-offs: (i) waist circumference >88 cm for women and >102 cm for men, (ii) HDL-C <1.29 mmol/L for women and <1.03 mmol/L for men, (iii) systolic blood pressure >130 or diastolic >85 mmHg, (iv) fasting blood glucose >6.1 mmol/L. Results are presented as Mean ± SEM. BP: blood pressure, CRP: C-reactive protein, FBG: fasting blood glucose, MDA: malondialdehyde, MetS: metabolic syndrome, OGTT: oral glucose tolerance test; *p < 0.05 vs Controls, #p < 0.05 vs Healthy.
Back to article page