Table 3 Lipid profile and HDL composition of the study participants.

From: Altered proteome of high-density lipoproteins from paediatric acute lymphoblastic leukemia survivors

 

Controls

ALL Survivors

All

Healthy

Unhealthy

TG (mmol/L)

0.90 ± 0.08

1.30 ± 0.36

0.79 ± 0.10

1.82 ± 0.69

TC (mmol/L)

4.24 ± 0.15

4.46 ± 0.21

4.10 ± 0.22

4.82 ± 0.32

LDL-C (mmol/L)

2.27 ± 0.12

2.59 ± 0.16

2.22 ± 0.15

3.00 ± 0.20**##

HDL-C (mmol/L)

Men

1.41 ± 0.11

1.11 ± 0.09

1.29 ± 0.12

0.93 ± 0.03*

Women

1.71 ± 0.08

1.42 ± 0.14

1.76 ± 0.11

1.07 ± 0.05**##

All

1.56 ± 0.09

1.26 ± 0.09

1.53 ± 0.12

1.00 ± 0.04**###

Non-HDL-C (mmol/L)

2.68 ± 0.15

3.20 ± 0.24

2.58 ± 0.14

3.82 ± 0.33*##

Ratio TC/HDL-C

2.8 ± 0.2

3.8 ± 0.3

2.8 ± 0.2

4.9 ± 0.4***###

% HDL

Triglycerides

1.95 ± 0.29

2.55 ± 0.89

1.33 ± 0.23

3.76 ± 1.72

Free Cholesterol

3.93 ± 0.21

3.33 ± 0.12*

3.62 ± 0.09

3.04 ± 0.17***##

Esterified Cholesterol

19.66 ± 1.12

17.51 ± 0.56

18.74 ± 0.64

16.28 ± 0.70**#

Phospholipids

29.83 ± 1.28

29.00 ± 0.96

29.12 ± 1.20

28.88 ± 1.59

Proteins

44.63 ± 1.55

47.62 ± 1.21

47.20 ± 1.40

48.05 ± 2.06

Weight ratio

0.28 ± 0.02

0.25 ± 0.01*

0.25 ± 0.01

0.25 ± 0.02

  1. Lipid profile and HDL were obtained from ALL survivors (n = 16) and age- and gender-matched controls (n = 8). ALL survivors were stratified in 2 groups according to their metabolic status as described in Methods (n = 8/group). Results are presented as Mean ± SEM. HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; TC: total cholesterol; TG: triglycerides; *p < 0.05, **p < 0.01, ***P < 0.001 vs Controls; #p < 0.05, ##p < 0.01, ###p < 0.001 vs Healthy.
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