Figure 1
Effect of treatment with vancomycin for seven days on gut microbiota. (a) Alpha-diversity of the gut microbiota. Shannon index calculated from the observed OTU numbers of intestinal microbiota samples from control and vancomycin-treated mice. (b) Relative abundance of intestinal bacteria. The relative abundance of each bacterial genus was analyzed by next-generation sequencing of bacterial 16S rDNA. The results are presented as the mean ± SE (n = 3 in each group). Significant differences between the control and vancomycin-treated groups at *P < 0.01 and **P < 0.001. Statistical significance was determined by Welch’s t test with Benjamini-Hochberg correction.
