Figure 7

Effect of vancomycin-induced gut microbiota alteration on colonic GPR43 expression in germ-free (GF) mice. (a) Immunostaining for GPR43 in the colonic mucosa of GF mice subjected to fecal transplantation (FT) using material from vancomycin-treated mice (FT-V) or from control mice (FT-C). Arrows indicating positive cells. (b) The number of GPR43-positive cells in the colonic mucosa. (c) Expression of GPR43 mRNA in colon tissues. Results are expressed as the mean ± SE (n = 4 in each group). Significantly greater than GF mice with FT-C: *P < 0.05.