Figure 2
From: Pro-angiogenic Ginsenosides F1 and Rh1 Inhibit Vascular Leakage by Modulating NR4A1
F1 and Rh1 regulate expression of angiogenesis-related genes differently from VEGF. (A,C) Venn diagrams show the overlapping subsets of differentially expressed genes (DEGs) for cell proliferation (A) and for cell migration-related genes (C) in VEGF, F1 and Rh1 treatment versus DMSO-treated control sample (Fold change |log2| ≥0.5, P-value < 0.1). Overlapping DEGs list are indicated in the table below with the same color as the Venn diagram intersections in A and C. (B,D) Heatmap representation showing gene expression changes of DEG subsets for cell proliferation (B) and for cell migration-related genes (D) in VEGF, F1 or Rh1 treatment group versus DMSO control group. Expression levels were shown as relative values (log2) normalized to DMSO-treated control sample. Red, up-regulated; blue, down-regulated.
