Table 1 Diseases associated with Lyme, analyzed as CCS-single-level categories (p value < 0.1).

From: Lyme Disease Patient Trajectories Learned from Electronic Medical Data for Stratification of Disease Risk and Therapeutic Response

Time (year)

Direction

Disease (CCS)

Lyme First

Disease First

Same Time

P value

Prob.

2

Coronary atherosclerosis and other heart disease

18

58

17

1.10E-02

0.62

2

Administrative/social admission

41

66

9

8.17E-02

0.57

2

+

Acute bronchitis

23

11

3

9.39E-02

0.62

5

HIV infection

2

21

9

5.51E-02

0.66

5

Coronary atherosclerosis and other heart disease

38

80

17

1.92E-02

0.59

5

Administrative/social admission

55

88

9

3.09E-02

0.58

5

Disorders of lipid metabolism

117

269

111

3.63E-02

0.54

5

+

Open wounds of extremities

24

6

0

7.15E-04

0.8

5

+

Open wounds of head; neck; and trunk

19

9

0

4.36E-02

0.68

5

+

Fracture of lower limb

16

8

0

7.58E-02

0.67

5

+

Cataract

57

21

10

3.67E-03

0.65

5

+

Fracture of upper limb

18

9

1

9.25E-02

0.64

5

+

Acute bronchitis

36

17

3

2.20E-02

0.64

5

+

Anal and rectal conditions

26

11

5

8.21E-02

0.62

5

+

Nonmalignant breast conditions

60

36

7

5.72E-02

0.58

5

+

Other eye disorders

75

41

14

4.76E-02

0.58

5

+

Neoplasms of unspecified nature or uncertain behavior

60

39

6

8.58E-02

0.57

5

+

Blindness and vision defects

58

33

11

9.89E-02

0.57

5

+

Nutritional deficiencies

219

141

47

6.85E-02

0.54

10

HIV infection

2

25

9

1.44E-02

0.69

10

Coronary atherosclerosis and other heart disease

44

91

17

9.18E-03

0.6

10

Administrative/social admission

61

97

9

2.20E-02

0.58

10

Disorders of lipid metabolism

121

301

111

1.59E-03

0.56

10

Essential hypertension

96

271

124

1.20E-02

0.55

10

+

Open wounds of extremities

28

7

0

2.54E-04

0.8

10

+

Maintenance chemotherapy; radiotherapy

14

5

1

5.77E-02

0.7

10

+

Cataract

64

26

10

3.32E-03

0.64

10

+

Occlusion or stenosis of precerebral arteries

22

10

3

8.77E-02

0.63

10

+

Acute bronchitis

37

19

3

3.37E-02

0.63

10

+

Poisoning by other medications and drugs

24

7

8

9.98E-02

0.62

10

+

Anal and rectal conditions

29

14

5

9.67E-02

0.6

10

+

Other eye disorders

87

43

14

7.69E-03

0.6

10

+

Nonmalignant breast conditions

65

41

7

6.60E-02

0.58

10

+

Blindness and vision defects

63

36

11

7.62E-02

0.57

10

+

Inflammation; infection of eye (except that caused

78

39

20

6.19E-02

0.57

  

by tuberculosis or sexually transmitted disease)

     

10

+

Nutritional deficiencies

228

143

47

3.51E-02

0.55

  1. A total of 275 diseases were tested.