Figure 2 | Scientific Reports

Figure 2

From: A critical regulator of Bcl2 revealed by systematic transcript discovery of lncRNAs associated with T-cell differentiation

Figure 2

Correlation between lncRNAs and mRNAs regulation in P5424 cells. (A) The functional annotation (biological processes) of coding genes which are associated with PMA/ionomycin-regulated lncRNAs, using the GREAT tool. The top 15 most significant terms are indicated. The inverted Log10 of the Binomial P value is represented. (B) Scatter plot depicting the Log2 (fold-change between PMA/ionomycin and DMSO) of regulated mRNA/lncRNA pairs in respect to the distance between their TSSs (Kb). Pairs separated by less than 100 kb, 200 kb and 500 Kb are displayed. Typical examples are highlighted in red. (C) Bar plot displaying the number of regulated lncRNAs (x-axis) according to the expression state (induced/repressed) of their closest mRNA and in terms of the distance between them (y-axis).

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