Table 4 Summary of PCT values to predict AKI.

From: Association between acute kidney injury and serum procalcitonin levels and their diagnostic usefulness in critically ill patients

PCT (ng/ml)a

Clinical condition

PCT threshold (ng/ml)

AUC

Sensitivity

95% CI

Specificity

95% CI

+LR

−LR

<0.05

Healthy

        

0.05~0.5

Local infection

0.05

0.561

0.744

0.688–0.796

0.378

0.336–0.421

1.196

0.677

0.5~2.0

Systemic infection (sepsis)

0.5

0.573

0.549

0.487–0.610

0.597

0.554–0.640

1.362

0.755

2.0~10

Severe sepsis

2.0

0.549

0.380

0.318–0.437

0.721

0.681–0.759

1.362

0.860

>10

Septic shock

10

0.544

0.229

0.180–0.285

0.863

0.830–0.891

1.672

0.893

Cut-off valueb

 

0.315

0.589

0.609

0.548–0.668

0.569

0.525–0.612

1.413

0.687

  1. Abbreviations: PCT, procalcitonin; AUC, area under curve; +LR, positive likelihood ratio; −LR, negative likelihood ratio. aCommonly used PCT threshold in clinical practice. bThreshold developed using the Youden method.
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